Erectile dysfunction or male impotence means unable to erect or maintain adequate sexual erection. A condition in which a person cannot erect or lose an erection during sexual intercourse is medically known as erectile dysfunction.
Erectile dysfunction is common in adult males because almost all men sometimes have difficulty erecting or maintaining an erection at some point in their lives. For most people, this is a temporary condition that disappears with little or no treatment. But for some people, this can be a persistent problem and therefore requires medical intervention.
This is considered a problem if it is difficult to maintain or maintain an erection more than 25% of the time. The problem may be psychological or physical. This can be determined by counting the number of night erections. Usually, men erect 3 to 5 times a night for up to 30 minutes. In most men, sexual desire is not affected by erectile difficulties. Physical causes are more common in older men, and psychological causes are more common in young men. In addition, erectile problems become more common with age, but they affect men of any age.
An erection requires the interaction of the brain, nerves, hormones and blood vessels. Anything that interferes with normal physiological processes can be a problem. Common reasons include:
- Conditions and diseases such as diabetes, high blood pressure, heart or thyroid disease, poor circulation, low testosterone, depression, spinal cord, nerve damage (eg, due to prostate surgery) Parkinson’s). disease)
- Drugs such as drug blood pressure (especially beta blockers), drugs for the heart (such as digoxin), certain drugs for digestive ulcers, sleeping pills and antidepressants.
- Nicotine, alcohol or cocaine.
- Poor communication with partners
- Stress, fear, anxiety or anger.
- Unrealistic sexual expectations
- “vicious circle” of suspicion, failure or negative communication, strengthening erection
Drug for the treatment of erectile dysfunction
In men who have recently (6-8 in the past few weeks) or significant hypotension, uncontrolled high blood pressure, unstable angina pectoris or myocardial infarction using drugs for erectile dysfunction, is not recommended. Severe heart failure, severe liver failure, or end-stage renal disease requiring dialysis. But others can use the drug safely under medical supervision.
The type 5 phosphodiesterase inhibitor (PDE-5) acts by improving the action of nitric oxide. As a result, the smooth corpus cavernosum of the penis relaxes and causes the formation of vasodilation in the corpus cavernosum. All of these effects are mediated by cyclic guanosine monophosphate (cGMP). Inhibition of PDE-5 prolongs the effects of cGMP and subsequently increases nitric oxide levels. The three PDE5 inhibitors have a common mechanism of action and are only pharmacologically active when cGMP synthesis is activated. Therefore, the role of PDE5 inhibitors requires sexual arousal.
Oral PDE-5 inhibitors can reduce the incidence of adverse events. Despite vardenafil, tadalafil and sildenafil also improved erectile function, and the duration of action of the three drugs was significantly different. Sildenafil and vardenafil have a half-life of about 4 hours and a half-life of 17.5 hours for tadalafil. In addition, the pharmacokinetic properties of tadalafil and its selectivity for PDE isoenzymes reflect differences in molecular structure.
Cialis as a drug against impotence
Sexual problems and male impotence may be the intervention of a wonderful drug called Cialis. Cialis belongs to a class of drugs called PDE-5 inhibitors that are used to treat cases of impotence in men worldwide.
Cialis works in the same way as other erectile dysfunction drugs by blocking an enzyme called phosphodiesterase-5. This results in fewer side effects and is taken at lower doses. Cialis helps the smooth muscles of the penis relax and expand, allowing more blood to enter, resulting in faster and more erections. islands.
Cialis is an approved prescription drug for the treatment of erectile dysfunction. Pay attention to the severe doses of 10 and 20 mg. It should be done before the planned sexual activity, regardless of food, but sexual stimulation is necessary.
Cialis is not for everyone. Men who take nitrates and “alpha-blockers” should not take Cialis because these drugs in combination with Cialis can cause blood pressure to drop to dangerous levels.
Advantages of Cialis compared to other impotence drugs
Cialis takes you outside the world of drugs in Yangshuo. It may be the only erectile dysfunction drug that has certain advantages over other oral erectile dysfunction drugs. Lux:
- Working hours of up to 36 hours, so you can have sex at a leisurely pace in a relaxed environment
- Cialis can be given without food, while other erectile dysfunction drugs have a dose limit after high fat meals
- Cialis has a different chemical structure, while the other two drugs for erectile dysfunction have similar molecular structures.
- For some men, it takes only 30 minutes to complete quickly.
- Effective under mild, moderate and severe ED conditions
- Can be taken on an empty stomach, so there is no need to plan a meal
- It allows you to choose the right time for you and your partner as it has a 36 hour window
- Millions of people around the world use it.
Availability of Cialis
Cialis is now widely used in pharmacies in Europe and the United States. It is approved in these markets for the treatment of mild to severe erectile dysfunction in doses of 10 to 20 mg. The label for each market indicates that the product must be taken before the expected sexual activity, regardless of the food. Sexual stimulation is a necessary condition for Cialis work. According to the European label, the effectiveness of Cialis can last from 24 hours to 36 hours after taking the contraceptive.
The availability of Cialis has never been a problem. All you need is the correct prescription for a qualified doctor. This is crucial because sales and over-the-counter purchases are considered illegal. In addition, you can browse the availability of online pharmacies to be able to purchase Cialis online. Cialis online can purchase a small portion of the drug offline.
Buying Cialis online is easy because it’s cost-effective and efficient and saves energy because men don’t have to queue up before selling Cialis’ pharmacies. All you have to do is fill out a prescription form with all the details of your medical history. Based on these details, the doctor will decide if you are eligible for Cialis. In addition, it can even be delivered to your door in a cautious package.